Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854371 | 0.93 | AGTR1 (0.51) | AGTR1AGTR2LMNAHPGDALDH1A1 | |
| SCHEMBL8972068 | 0.86 | AGTR1 (0.60) | AGTR1AGTR2LMNATP53 | |
| SCHEMBL9851478 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL8560040 | 0.85 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9402019 | 0.85 | TSHR (0.48) | LMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL8563437 | 0.85 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8972057 | 0.84 | AGTR1 (0.71) | AGTR1AGTR2LMNA | |
| SCHEMBL9854484 | 0.83 | AGTR1 (0.49) | AGTR1AGTR2LMNAHPGDALDH1A1 | |
| SCHEMBL7622112 | 0.83 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL29486817 | 0.83 | AGTR1 (0.72) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |