Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724279 | 0.82 | GAA (0.44) | ALDH1A1GAACA12CA9ACE | |
| SCHEMBL141088 | 0.81 | TDP1 (0.42) | ALDH1A1SMN1; SMN2CA12CA9TDP1 | |
| SCHEMBL16265022 | 0.80 | KMT2A (0.47) | ALDH1A1SMN1; SMN2GAACA12CA9 | |
| SCHEMBL8746370 | 0.77 | GAA (0.39) | ALDH1A1SMN1; SMN2GAACA12CA9 | |
| SCHEMBL28255718 | 0.77 | TDP1 (0.45) | ALDH1A1SMN1; SMN2GAACA12CA9 | |
| SCHEMBL21538597 | 0.75 | ADH1B (0.44) | SMN1; SMN2ACETDP1CTSKCAPN1 | |
| SCHEMBL28099192 | 0.75 | SIGMAR1 (0.47) | ACECTSKTRPA1 | |
| SCHEMBL21891545 | 0.74 | CA12 (0.47) | ALDH1A1SMN1; SMN2CA12CA9TDP1 | |
| SCHEMBL6049418 | 0.72 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAACA12CA9 | |
| SCHEMBL10952614 | 0.72 | GAA (0.50) | ALDH1A1SMN1; SMN2GAACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |