Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728490 | 0.90 | KLK5 (0.55) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL29469017 | 0.90 | ACE (0.59) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL9956671 | 0.90 | ACE (0.59) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL2727573 | 0.90 | ACE (0.59) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL6674426 | 0.90 | KLK5 (0.55) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL9956668 | 0.90 | ACE (0.59) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL2727571 | 0.90 | ACE (0.59) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL15715615 | 0.88 | CTSS (0.53) | RENCTSSCTSKCTSBITGA4 | |
| SCHEMBL10209857 | 0.87 | ITGA4 (0.48) | CTSSCTSKCTSBITGA4ITGB7 | |
| SCHEMBL4733108 | 0.87 | ITGA4 (0.50) | CTSSCTSKCTSBITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |