Sugi Predict

Sugi Predict / Compounds / SCHEMBL29469017

SCHEMBL29469017

SCHEMBL29469017

CC(C)(C)OC(=O)N[C@@H](Cc1cccc([N+](=O)[O-])c1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.59
▸ PPARA Q07869 3/20 0.55
▸ PPARG P37231 2/20 0.55
▸ CTSS P25774 5/20 0.53
▸ CTSK P43235 4/20 0.53
▸ CTSB P07858 3/20 0.53
▸ ITGA4 P13612 1/20 0.53
▸ ITGB7 P26010 1/20 0.53
▸ CTSL P07711 2/20 0.52
▸ PTPN1 P18031 1/20 0.49
▸ MAPT P10636 2/20 0.49
▸ ALOX5 P09917 1/20 0.49
▸ NPC1 O15118 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ ITGB3 P05106 2/20 0.48
▸ ITGA2B P08514 2/20 0.48
▸ ITGB1 P05556 1/20 0.48
▸ ITGAV P06756 1/20 0.48
▸ ITGB5 P18084 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2727571 1.00 ACE (0.59) ACEPPARAPPARGCTSSCTSK
SCHEMBL9956671 1.00 ACE (0.59) ACEPPARAPPARGCTSSCTSK
SCHEMBL2727573 1.00 ACE (0.59) ACEPPARAPPARGCTSSCTSK
SCHEMBL9956668 1.00 ACE (0.59) ACEPPARAPPARGCTSSCTSK
SCHEMBL2728490 0.91 KLK5 (0.55) ACEPPARAPPARGCTSSCTSK
SCHEMBL6674426 0.91 KLK5 (0.55) ACEPPARAPPARGCTSSCTSK
SCHEMBL9854733 0.90 REN (0.52) ACEPPARAPPARGCTSSCTSK
SCHEMBL15715615 0.89 CTSS (0.53) ACEPPARAPPARGCTSSCTSK
SCHEMBL29551208 0.88 ITGA4 (0.53) ACEPPARACTSSCTSKCTSB
SCHEMBL4733108 0.88 ITGA4 (0.50) ACEPPARAPPARGCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630808-B2 Modified archaeal family b polymerases Singular Genomics Systems, Inc. (US) 2026-05-19 — — US disclosed
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 — — US disclosed
US-12454683-B2 Modified archaeal family B polymerases Singular Genomics Systems, Inc. (US) 2025-10-28 — — US disclosed
US-20250283138-A1 BIOREACTIVE COMPOUNDS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-11 — — US disclosed
EP-4612127-A1 BIOREACTIVE PROTEINS CONTAINING UNNATURAL AMINO ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-10 — — EP disclosed
US-12344867-B2 Engineered Pyrococcus enzymes and uses thereof Singular Genomics Systems, Inc. (US) 2025-07-01 — — US disclosed
WO-2025128629-A1 UNNATURAL AMINO ACIDS, BIOREACTIVE PROTEINS, AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-06-19 — — WO disclosed
CN-119752820-A Bioreactive compositions and methods of use thereof 加利福尼亚大学董事会 2025-04-04 — — CN disclosed
US-20250101465-A1 ADENO-ASSOCIATED VIRUS COMPOSITIONS AND METHODS OF USE THEREOF CITY OF HOPE 2025-03-27 — — US disclosed
US-20250084121-A1 BIOREACTIVE COMPOSITIONS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-03-13 — — US disclosed
WO-2022236176-A2 FXA PROTEIN FOR TREATING AND/OR PREVENTING COVID-19 CITY OF HOPE (US) 2022-11-10 — — WO disclosed
WO-2022232377-A2 BIOREACTIVE PROTEINS CONTAINING UNNATURAL AMINO ACIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-11-03 — — WO disclosed
EP-4081254-A1 STABILIZATION OF MHC COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-11-02 — — EP disclosed
US-20220282230-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES FIRST-CITIZENS BANK & TRUST COMPANY 2022-09-08 — — US disclosed
US-20220242963-A1 B-CELL ACTIVATING CD73 ANTIBODIES CORVUS PHARMACEUTICALS, INC. 2022-08-04 — — US disclosed
WO-2022112942-A2 ANTI-CD48 ANTIBODIES, ANTIBODY DRUG CONJUGATES, AND USES THEREOF NOVARTIS AG (CH) 2022-06-02 — — WO disclosed
US-20220136048-A1 METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES FIRST-CITIZENS BANK & TRUST COMPANY 2022-05-05 — — US disclosed
WO-2022094415-A1 METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES Singular Genomics Systems, Inc. (US) 2022-05-05 — — WO disclosed
US-20220119780-A1 ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2022-04-21 — — US disclosed
US-20220119779-A1 MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2022-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630808-B2 Modified archaeal family b polymerases SSU72, POLB, POLQ ACE 1258/4885PPARA 1934/4885PPARG 2577/4885
US-20220242963-A1 B-CELL ACTIVATING CD73 ANTIBODIES ENTPD1, NT5E, ENTPD5 ACE 4529/4885PPARA 3898/4885PPARG 4354/4885
US-20250283138-A1 BIOREACTIVE COMPOUNDS AND METHODS OF USE THEREOF BCAT2, BCAT1, AADAT ACE 93/4885PPARA 1506/4885PPARG 3044/4885
US-20250101465-A1 ADENO-ASSOCIATED VIRUS COMPOSITIONS AND METHODS OF USE THEREOF F8, ACTR8, ZCCHC8 ACE 573/4885PPARA 3198/4885PPARG 3996/4885
US-20250084121-A1 BIOREACTIVE COMPOSITIONS AND METHODS OF USE THEREOF BCAT2, AADAT, BCAT1 ACE 584/4885PPARA 2072/4885PPARG 3429/4885
US-20260125660-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES DNMT3A, POLB, POLM ACE 663/4885PPARA 2986/4885PPARG 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.