SCHEMBL9855003

SCHEMBL9855003

OCC1OC(c2ncc3nc[nH]c3n2)C1CO

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914676 0.85 PYGL (0.41) MEN1KMT2A
SCHEMBL17364274 0.85 PYGL (0.41) MEN1KMT2A
SCHEMBL745559 0.85 PYGL (0.41) MEN1KMT2A
SCHEMBL3727543 0.85 PYGL (0.41) MEN1KMT2A
SCHEMBL6935271 0.85 PYGL (0.41) MEN1KMT2A
SCHEMBL10666441 0.85 PYGL (0.41) MEN1KMT2A
SCHEMBL3664019 0.85 PYGL (0.41) MEN1KMT2A
SCHEMBL9855014 0.78 ALDH1A1 (0.40)
SCHEMBL7170419 0.71 ADK (0.33)
SCHEMBL6746376 0.69 TSHR (0.50) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433898-A2 Analogs of oxetanyl purines and pyrimidines ABBOTT LABORATORIES (US) 1991-06-26 EP disclosed