Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199070 | 0.85 | PYGL (0.41) | ALDH1A1KDM4E | |
| SCHEMBL27552331 | 0.85 | PYGL (0.41) | ALDH1A1KDM4E | |
| SCHEMBL27948335 | 0.85 | PYGL (0.41) | ALDH1A1KDM4E | |
| SCHEMBL25170485 | 0.84 | PYGL (0.43) | ALDH1A1KDM4E | |
| SCHEMBL27734445 | 0.82 | KDM4E (0.36) | ALDH1A1KDM4ERXFP1CDK2PAK1 | |
| SCHEMBL9855003 | 0.78 | MEN1 (0.30) | — | |
| SCHEMBL8771925 | 0.69 | ALDH1A1 (0.41) | ALDH1A1KDM4ERXFP1CDK2PAK1 | |
| 2-Aminopurine SCHEMBL28775710 | 0.68 | ALDH1A1 (0.59) | ALDH1A1KDM4ERXFP1PAK1 | |
| SCHEMBL27868963 | 0.68 | ALDH1A1 (0.40) | ALDH1A1KDM4ERXFP1CDK2PAK1 | |
| SCHEMBL9855009 | 0.67 | GRIN2B (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433898-A2 | Analogs of oxetanyl purines and pyrimidines | ABBOTT LABORATORIES (US) | 1991-06-26 | — | — | EP | disclosed |