Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855625 | 0.74 | PTPN1 (0.48) | PLOD2CES2CES1RAB9ANPC1 | |
| SCHEMBL9855569 | 0.72 | CA12 (0.40) | CES2CES1CA12MMP2RAB9A | |
| SCHEMBL9855767 | 0.63 | PLOD2 (0.42) | PLOD2CES2CES1RAB9ANPC1 | |
| SCHEMBL16823 | 0.62 | CES1 (0.62) | PLOD2CES2CES1RAB9ANPC1 | |
| Phosphoric Acid SCHEMBL5148554 | 0.62 | LTA4H (0.61) | CES2CES1RAB9ANPC1PTPN1 | |
| SCHEMBL1486788 | 0.61 | PGK1 (0.59) | CA12MMP2 | |
| SCHEMBL11050791 | 0.61 | CES2 (0.54) | CES2CES1RAB9ANPC1PTPN1 | |
| Trifluoroacetic Acid SCHEMBL27664698 | 0.61 | PLOD2 (0.53) | PLOD2RAB9ANPC1PTPN1CA1 | |
| SCHEMBL25142224 | 0.59 | PLOD2 (0.52) | PLOD2CES2CES1RAB9ANPC1 | |
| SCHEMBL10484473 | 0.59 | CES1 (0.42) | PLOD2CES2CES1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |