Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TPMT | P51580 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189692 | 0.88 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAATPMTHPGD | |
| SCHEMBL30822595 | 0.88 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAATPMTHPGD | |
| SCHEMBL10322834 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL10323753 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL5230795 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL6343891 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL1191343 | 0.83 | TPMT (0.79) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL10323382 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL10323754 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAATPMTTAS1R3 | |
| SCHEMBL1191207 | 0.81 | TPMT (0.54) | ALDH1A1KDM4EGAATPMTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462557-A | Preparation method of key intermediate of dorranolazine | 上海博悦生物科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-122059904-A | Synthetic multi-substituted method for preparing North Rate | 重庆圣华曦药业股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20250376457-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM INC (US) | 2025-12-11 | — | — | US | disclosed |
| CN-120398788-A | Preparation method of key intermediate of dorranolazine | 广东赛烽医药科技有限公司 | 2025-08-01 | — | — | CN | disclosed |
| CN-120058634-A | Multi-tenor preparation method of mine | 南京佰麦生物技术有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119591561-A | Multi-tenor Synthesis method of thunder | 上海药坦药物研究开发有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119504641-A | Multi-tenor preparation method of mine | 南京唯创远医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119462557-A | Preparation method of key intermediate of dorranolazine | 上海博悦生物科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119462557-A | Preparation method of key intermediate of dorranolazine | 上海博悦生物科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119080698-A | Aroyl nuciferine derivative for inhibiting URAT1 as well as preparation method and application thereof | 山东省农业科学院 | 2024-12-06 | — | — | CN | disclosed |
| WO-2013074930-A1 | METHODS FOR TREATING LEISHMANIASIS | HOWARD UNIVERSITY (US) | 2013-05-23 | — | — | WO | disclosed |
| US-8367843-B2 | Phenol derivative | FUJI YAKUHIN CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| WO-2013016661-A1 | METHOD FOR INHIBITING TRYPANSOMA CRUZI | HOWARD UNIVERSITY (US) | 2013-01-31 | — | — | WO | disclosed |
| EP-2484669-A1 | NOVEL PHENOL DERIVATIVE | Fuji Yakuhin Co., Ltd. (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120184587-A1 | NOVEL PHENOL DERIVATIVE | FUJI YAKUHIN CO., LTD. (JP) | 2012-07-19 | — | — | US | disclosed |
| US-20120149778-A1 | COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE | 2012-06-14 | — | — | US | disclosed |
| EP-2440522-A2 | AROYLTHIOUREA AND ARYLTHIOCARBONYLUREA DERIVATIVES | University Court of The University of Dundee (GB) | 2012-04-18 | — | — | EP | disclosed |
| US-7875631-B2 | e.g.1-(3,5-dichlorophenyl)-2-formyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline; to prevent and/or treat cancer and other abnormal cell growth, and metabolic as well as blood vessel proliferate disorders, in which uncontrolled expression of insulin-like growth factor-1 receptor is observed | ANALYTECON S.A. (CH) | 2011-01-25 | — | — | US | disclosed |
| WO-2010142956-A2 | COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-12-16 | — | — | WO | disclosed |
| US-3964896-A | Oxadiazole benzoic acid derivatives as herbicides | UNIROYAL, INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250376457-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | ALDH1A1 174/4885KDM4E 3481/4885GAA 739/4885 |
| US-20120149778-A1 | COMPOUNDS | AR, NR5A1, NAT1 | ALDH1A1 253/4885KDM4E 1689/4885GAA 2147/4885 |
| US-20120184587-A1 | NOVEL PHENOL DERIVATIVE | XDH, REN, UTS2R | ALDH1A1 74/4885KDM4E 2141/4885GAA 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.