Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935603 | 0.71 | CES2 (0.44) | CES2CES1LMNAPTBP1SMN1; SMN2 | |
| SCHEMBL21281501 | 0.69 | CES2 (0.52) | CES2CES1LMNAPTBP1SMN1; SMN2 | |
| SCHEMBL8828837 | 0.69 | CES2 (0.52) | CES2CES1LMNAPTBP1SMN1; SMN2 | |
| SCHEMBL1515113 | 0.69 | CES2 (0.52) | CES2CES1LMNAPTBP1SMN1; SMN2 | |
| SCHEMBL8828839 | 0.69 | CES2 (0.52) | CES2CES1LMNAPTBP1SMN1; SMN2 | |
| SCHEMBL9855130 | 0.68 | CES2 (0.41) | CES2CES1LMNASMN1; SMN2CA1 | |
| SCHEMBL9855452 | 0.68 | PTPN1 (0.48) | CES2CES1SMN1; SMN2CA1CA2 | |
| SCHEMBL25501693 | 0.68 | ACHE (0.59) | CES2CES1LMNAPTBP1SMN1; SMN2 | |
| SCHEMBL9855767 | 0.68 | PLOD2 (0.42) | CES2CES1LMNAPTBP1SMN1; SMN2 | |
| SCHEMBL25501695 | 0.68 | ESR1 (0.47) | CES2CES1LMNAPTBP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |