Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SDCBP | O00560 | 1/20 | 0.33 |
| ▸ | SDC2 | P34741 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400659 | 0.83 | MAOA (0.44) | MAOAMEN1KMT2ACYP2A6SMN1; SMN2 | |
| SCHEMBL27944855 | 0.80 | MAOA (0.44) | MAOAMEN1KMT2ARAB9ACYP2A6 | |
| SCHEMBL9856484 | 0.78 | ESR1 (0.45) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9856255 | 0.78 | HTT (0.34) | HTT | |
| SCHEMBL12860701 | 0.78 | SLC6A4 (0.39) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL10144008 | 0.78 | TSHR (0.50) | MEN1KMT2ARAB9ASMN1; SMN2HTT | |
| SCHEMBL11309197 | 0.78 | MAPK1 (0.42) | MAOAMEN1KMT2ARAB9AHTT | |
| SCHEMBL10394300 | 0.78 | SLC6A4 (0.50) | MAOARAB9AHTTMAOB | |
| SCHEMBL10473468 | 0.77 | MAOA (0.40) | MAOAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1453904 | 0.77 | L3MBTL1 (0.45) | MAOAMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |