Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | TXN | P10599 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856484 | 0.78 | ESR1 (0.45) | HTTTSHRSLC6A4 | |
| SCHEMBL12860701 | 0.78 | SLC6A4 (0.39) | HTTTSHRSLC6A4 | |
| SCHEMBL9855446 | 0.78 | MAOA (0.47) | HTT | |
| SCHEMBL10144008 | 0.78 | TSHR (0.50) | HTTTSHR | |
| SCHEMBL10394300 | 0.78 | SLC6A4 (0.50) | HTTSLC6A4 | |
| SCHEMBL11309197 | 0.78 | MAPK1 (0.42) | HTTTSHRSLC6A4 | |
| SCHEMBL1453904 | 0.77 | L3MBTL1 (0.45) | HTTSLC6A4 | |
| SCHEMBL18245186 | 0.77 | HTT (0.33) | HTTTSHRSLC6A4TXNTXNRD1 | |
| SCHEMBL10014257 | 0.77 | ADRA2A (0.40) | HTTTSHRSLC6A4TXNTXNRD1 | |
| Fluoride SCHEMBL1335974 | 0.76 | MAOA (0.47) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4661617-A | PESTICIDES | SANDOZ LTD. (CH) | 1987-04-28 | — | — | US | disclosed |
| US-4590282-A | Pest control agents | SANDOZ LTD. (CH) | 1986-05-20 | — | — | US | disclosed |