Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789227 | 0.81 | GABRA1 (0.37) | SMN1; SMN2KMT2APGRGABRA1GABRG2 | |
| SCHEMBL12431240 | 0.80 | NISCH (0.51) | NISCHALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4795842 | 0.80 | GABRA1 (0.54) | NISCHSMN1; SMN2LMNAPGRMAPT | |
| SCHEMBL9855192 | 0.79 | NISCH (0.53) | NISCHRAB9ANPC1KMT2APGR | |
| SCHEMBL11787892 | 0.74 | RAB9A (0.42) | NISCHALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL16661272 | 0.72 | PIK3CD (0.41) | ALDH1A1RAB9ANPC1HTTMEN1 | |
| SCHEMBL12348434 | 0.70 | GABRA1 (0.44) | NISCHALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7841987 | 0.69 | NISCH (0.53) | NISCHALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL4991544 | 0.68 | AKT2 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9855245 | 0.65 | NISCH (0.47) | NISCHALDH1A1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158000-B1 | REGIO AND OPTICAL ISOMERS OF IMIDAZOLINYL TOLUIC ACIDS, ESTERS AND SALTS, THEIR METHOD OF PREPARATION AND THEIR USE AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |