Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855240 | 0.96 | DRD2 (0.41) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL9855509 | 0.96 | DRD2 (0.43) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL9855133 | 0.95 | DRD2 (0.42) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL9854961 | 0.95 | DRD2 (0.43) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL10511457 | 0.94 | DRD2 (0.40) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL9854881 | 0.94 | DRD2 (0.43) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL10511742 | 0.93 | DRD2 (0.40) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL9855639 | 0.92 | DRD3 (0.45) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL10512625 | 0.92 | TSHR (0.41) | DRD2DRD4DRD3ACACBFFAR1 | |
| SCHEMBL9854923 | 0.91 | DRD2 (0.41) | DRD2DRD4DRD3ACACBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |