Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 17/20 | 0.38 |
| ▸ | THRB | P10828 | 17/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8133800 | 0.99 | THRA (0.38) | THRATHRBAPPHRH3 | |
| SCHEMBL9856009 | 0.89 | THRA (0.37) | THRATHRB | |
| Hydrochloric Acid SCHEMBL8127558 | 0.88 | THRA (0.36) | THRATHRB | |
| SCHEMBL8132522 | 0.82 | DNM2 (0.40) | THRATHRB | |
| SCHEMBL9855576 | 0.81 | THRA (0.42) | THRATHRB | |
| Hydrochloric Acid SCHEMBL8120665 | 0.80 | THRA (0.41) | THRATHRB | |
| SCHEMBL9855915 | 0.80 | THRB (0.37) | THRATHRB | |
| SCHEMBL8126443 | 0.80 | PDE4A (0.34) | THRATHRB | |
| SCHEMBL9855823 | 0.80 | THRA (0.39) | THRATHRB | |
| Hydrochloric Acid SCHEMBL9291047 | 0.80 | DNM2 (0.39) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427765-A1 | ALKOXY-4(1H)-PYRIDONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USE AS DRUGS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-05-22 | — | — | EP | disclosed |
| WO-1990001477-A1 | ALKOXY-4(1H)-PYRIDONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USE AS DRUGS | Gödecke Aktiengesellschaft (DE) | 1990-02-22 | — | — | WO | disclosed |
| EP-0354495-A1 | Alkoxy-4(1H)-pyridone derivatives, process for their preparation and their pharmaceutical use | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-02-14 | — | — | EP | disclosed |