Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855111 | 0.78 | CES2 (0.38) | ALDH1A1HPGDPOLBCA1CA2 | |
| SCHEMBL9300976 | 0.77 | CES2 (0.40) | ALDH1A1HPGDHTR7LMNACA1 | |
| SCHEMBL9855130 | 0.72 | CES2 (0.41) | ALDH1A1HPGDLMNACA1CA2 | |
| SCHEMBL9855083 | 0.67 | HTR7 (0.42) | ALDH1A1HPGDHTR7POLBGAA | |
| SCHEMBL9855611 | 0.67 | CYP1A2 (0.35) | ALDH1A1HPGDDPP4CA1CA2 | |
| SCHEMBL9855430 | 0.67 | CYP1A2 (0.35) | ALDH1A1HPGDDPP4CA1CA2 | |
| SCHEMBL12224069 | 0.66 | ALDH1A1 (0.46) | ALDH1A1HPGDSLC6A2SLC6A3HTR7 | |
| SCHEMBL19003444 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HPGDSLC6A2SLC6A3HTR7 | |
| SCHEMBL9621919 | 0.66 | CYP1A2 (0.37) | ALDH1A1HPGDDPP4CA1CA2 | |
| SCHEMBL9621921 | 0.66 | CYP1A2 (0.37) | ALDH1A1HPGDDPP4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |