Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328217 | 0.85 | LTA4H (0.50) | LTA4HCYP3A4CYP2D6 | |
| SCHEMBL10850125 | 0.82 | TAAR1 (0.54) | TAAR1LTA4HPLA2G2ACYP19A1ESR1 | |
| SCHEMBL122883 | 0.82 | ACACB (0.45) | LTA4HACACB | |
| SCHEMBL9274036 | 0.81 | NR1I2 (0.53) | CYP19A1SMN1; SMN2CYP3A4ACACBALDH1A1 | |
| SCHEMBL9266350 | 0.81 | ACACB (0.40) | TDP1ACACBALDH1A1 | |
| SCHEMBL9270333 | 0.81 | ACACB (0.40) | SMN1; SMN2TDP1ACACBALDH1A1 | |
| SCHEMBL9856414 | 0.81 | NR1I2 (0.53) | CYP19A1SMN1; SMN2CYP3A4ACACBALDH1A1 | |
| SCHEMBL9856089 | 0.80 | ACACB (0.40) | LTA4HACACB | |
| SCHEMBL13328221 | 0.80 | CYP2D6 (0.56) | LTA4HCYP19A1SMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL10339063 | 0.80 | NR5A1 (0.58) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4960796-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0285934-A1 | Cyclopropane carboxamides | BASF Aktiengesellschaft (DE) | 1988-10-12 | — | — | EP | disclosed |
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |