Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122883 | 0.89 | ACACB (0.45) | ACACBMAPTMCHR1HDAC1HDAC2 | |
| SCHEMBL22563306 | 0.83 | ST14 (0.45) | ACACBLTA4H | |
| SCHEMBL6371042 | 0.83 | TDP1 (0.50) | ACACBMAPTMCHR1HDAC1HDAC2 | |
| SCHEMBL746308 | 0.83 | TDP1 (0.50) | ACACBMAPTMCHR1HDAC1HDAC2 | |
| SCHEMBL20133454 | 0.83 | ACHE (0.41) | MAPTMTNR1AMTNR1B | |
| SCHEMBL19286562 | 0.83 | TDP1 (0.47) | MAPTMTNR1AMTNR1B | |
| SCHEMBL12521736 | 0.82 | ALDH1A3 (0.48) | ACACBMAPTMCHR1PARP10 | |
| SCHEMBL18260758 | 0.81 | SLC6A4 (0.39) | MTNR1AMTNR1BPARP10 | |
| SCHEMBL3592279 | 0.81 | LDHA (0.42) | MAPTMTNR1AMTNR1B | |
| SCHEMBL6479568 | 0.81 | LDHA (0.42) | MAPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |