Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856319 | 0.87 | XBP1 (0.43) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL9856297 | 0.85 | ALDH1A1 (0.50) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL9856137 | 0.85 | ALDH1A1 (0.41) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL10394248 | 0.81 | MTNR1A (0.51) | ALDH1A1MTNR1AMTNR1BSMN1; SMN2ACACB | |
| SCHEMBL9856425 | 0.81 | ALDH1A1 (0.49) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL9856373 | 0.81 | MTNR1A (0.50) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL10395541 | 0.80 | ALDH1A1 (0.48) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL9856365 | 0.79 | L3MBTL1 (0.50) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL9856323 | 0.79 | ALDH1A1 (0.47) | ALDH1A1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL9856462 | 0.79 | USP2 (0.40) | ALDH1A1USP2ALOX15TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | claimed |
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |