Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394255 | 0.96 | USP2 (0.37) | USP2ALOX15TSHRMAPK1HSD17B10 | |
| SCHEMBL10394254 | 0.88 | MTNR1A (0.38) | USP2ALOX15TSHRMAPK1HSD17B10 | |
| SCHEMBL9856458 | 0.83 | MTNR1A (0.43) | USP2ALOX15TSHRMAPK1HSD17B10 | |
| SCHEMBL9856024 | 0.82 | LMNA (0.44) | MAPK1MTNR1AMTNR1BNPSR1SMN1; SMN2 | |
| SCHEMBL9856511 | 0.81 | L3MBTL1 (0.47) | USP2ALOX15TSHRMAPK1HSD17B10 | |
| SCHEMBL10394859 | 0.80 | MTNR1A (0.44) | TSHRMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL9855896 | 0.79 | L3MBTL1 (0.41) | TSHRALOX5PPARGPPARASMN1; SMN2 | |
| SCHEMBL9856429 | 0.79 | ALDH1A1 (0.43) | USP2ALOX15TSHRMAPK1HSD17B10 | |
| SCHEMBL9856153 | 0.78 | LMNA (0.41) | MAPK1MTNR1AMTNR1BNPSR1SMN1; SMN2 | |
| SCHEMBL9268024 | 0.78 | NR1I2 (0.49) | USP2MAPK1ALOX5PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | claimed |
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |