Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394911 | 0.93 | MAPK1 (0.53) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL9856365 | 0.90 | L3MBTL1 (0.50) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10794873 | 0.88 | SLC6A2 (0.50) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10795135 | 0.84 | CHRNB2 (0.44) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL9856673 | 0.83 | MAPT (0.49) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10895637 | 0.81 | ALDH1A1 (0.72) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL9856275 | 0.81 | L3MBTL1 (0.47) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11886540 | 0.81 | NPC1 (0.65) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10394215 | 0.80 | L3MBTL1 (0.46) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL9856035 | 0.79 | L3MBTL1 (0.59) | MAPK1SMN1; SMN2L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | claimed |
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |