Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 2/20 | 0.31 |
| ▸ | ALPI | P09923 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856564 | 0.80 | PTPN1 (0.37) | PTPN1SMN1; SMN2EPAS1LMNAMAPT | |
| SCHEMBL9575552 | 0.79 | PTPN1 (0.39) | PTPN1SMN1; SMN2EPAS1LMNAMAPT | |
| SCHEMBL10703230 | 0.77 | PTPN1 (0.38) | PTPN1SMN1; SMN2EPAS1LMNAMAPT | |
| SCHEMBL27728519 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2LMNAMAPTGAAKDM4E | |
| SCHEMBL28558259 | 0.71 | ALDH1A1 (0.49) | SMN1; SMN2EPAS1LMNAMAPTHTT | |
| SCHEMBL7454336 | 0.71 | MAPT (0.42) | SMN1; SMN2LMNAMAPTHTTGAA | |
| SCHEMBL10701358 | 0.70 | ALDH1A1 (0.47) | SMN1; SMN2LMNAMAPTGAAKDM4E | |
| SCHEMBL10535167 | 0.70 | TDP1 (0.49) | LMNAMAPTALDH1A1 | |
| SCHEMBL16095720 | 0.69 | PTPN1 (0.45) | PTPN1SMN1; SMN2EPAS1LMNAMAPT | |
| SCHEMBL3970948 | 0.68 | ALDH1A1 (0.45) | SMN1; SMN2LMNAMAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028728-A | Process for the preparation of reaction products of 2,2-bis-(4-hydroxphenyl)-hexafluoropropane and new derivatives of this type | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |