Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10703230 | 0.88 | PTPN1 (0.38) | PTPN1MASP2F2SMN1; SMN2EPAS1 | |
| SCHEMBL4649727 | 0.88 | LMNA (0.46) | PTPN1MASP2F2SMN1; SMN2LMNA | |
| SCHEMBL9856564 | 0.86 | PTPN1 (0.37) | PTPN1MASP2F2SMN1; SMN2EPAS1 | |
| SCHEMBL9575509 | 0.81 | MASP2 (0.41) | PTPN1MASP2F2SMN1; SMN2LMNA | |
| SCHEMBL9856562 | 0.79 | PTPN1 (0.37) | PTPN1SMN1; SMN2EPAS1LMNAMAPT | |
| SCHEMBL10702712 | 0.76 | LMNA (0.44) | PTPN1MASP2F2SMN1; SMN2LMNA | |
| SCHEMBL9575360 | 0.74 | CA1 (0.43) | PTPN1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL16095720 | 0.72 | PTPN1 (0.45) | PTPN1MASP2F2SMN1; SMN2EPAS1 | |
| SCHEMBL3844085 | 0.71 | KMT2A (0.42) | SMN1; SMN2LMNAMAPK1HPGDMAPT | |
| SCHEMBL27731145 | 0.71 | HSPB1 (0.58) | SMN1; SMN2LMNAMAPK1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278414-B1 | PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | claimed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | claimed |
| EP-0278414-B1 | PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5028728-A | Process for the preparation of reaction products of 2,2-bis-(4-hydroxphenyl)-hexafluoropropane and new derivatives of this type | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |