Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575552 | 0.86 | PTPN1 (0.39) | PTPN1MASP2F2SMN1; SMN2EPAS1 | |
| SCHEMBL10703230 | 0.84 | PTPN1 (0.38) | PTPN1MASP2F2SMN1; SMN2EPAS1 | |
| SCHEMBL9856562 | 0.80 | PTPN1 (0.37) | PTPN1SMN1; SMN2EPAS1GAALMNA | |
| SCHEMBL4649727 | 0.74 | LMNA (0.46) | PTPN1MASP2F2SMN1; SMN2GAA | |
| SCHEMBL27728520 | 0.73 | MASP2 (0.44) | MASP2F2SMN1; SMN2GAALMNA | |
| SCHEMBL10702712 | 0.73 | LMNA (0.44) | PTPN1MASP2F2SMN1; SMN2GAA | |
| SCHEMBL8501372 | 0.72 | ALPL (0.41) | SMN1; SMN2GAALMNAMAPTHPGD | |
| SCHEMBL28558260 | 0.71 | ALDH1A1 (0.49) | SMN1; SMN2EPAS1GAALMNAMAPT | |
| SCHEMBL27679171 | 0.70 | MAPK1 (0.47) | SMN1; SMN2LMNAMAPTMAPK1HPGD | |
| SCHEMBL16095720 | 0.69 | PTPN1 (0.45) | PTPN1MASP2F2SMN1; SMN2EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028728-A | Process for the preparation of reaction products of 2,2-bis-(4-hydroxphenyl)-hexafluoropropane and new derivatives of this type | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |