Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036010 | 0.86 | KDM4E (0.53) | MAPTHPGDMEN1NR1I2LMNA | |
| SCHEMBL2955123 | 0.84 | HPGD (0.50) | MAPTHPGDKDM4EALDH1A1GAA | |
| SCHEMBL3895936 | 0.81 | L3MBTL1 (0.61) | MAPTHPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL4114408 | 0.80 | KDM4E (0.49) | MAPTHPGDMEN1NR1I2LMNA | |
| Valencic Acid SCHEMBL3316632 | 0.80 | PKM (0.53) | MAPTHPGDMEN1NR1I2LMNA | |
| SCHEMBL8045370 | 0.80 | GAA (0.49) | MAPTHPGDMEN1NR1I2LMNA | |
| SCHEMBL10805062 | 0.80 | NDUFS8 (0.53) | MAPTMEN1LMNASLC6A2SLC6A3 | |
| SCHEMBL10792097 | 0.79 | HTT (0.42) | HPGDKDM4EALDH1A1HTT | |
| SCHEMBL9856070 | 0.79 | MGAM (0.55) | LMNASLC6A2SLC6A3KDM4EALDH1A1 | |
| SCHEMBL9727736 | 0.79 | CYP19A1 (0.48) | KDM4EALDH1A1MTNR1AMAOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4647698-A | Novel compositions | SANDOZ LTD. (US) | 1987-03-03 | — | — | US | disclosed |