Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856741 | 0.88 | HTR2A (0.49) | HTR2AHRH1CHRM1ALDH1A1UBE2N | |
| SCHEMBL9856702 | 0.85 | TAAR1 (0.49) | HTR2AHRH1CHRM1SMN1; SMN2UBE2N | |
| SCHEMBL9857027 | 0.85 | HTR2A (0.49) | HTR2AHRH1CHRM1ALDH1A1LMNA | |
| SCHEMBL9856457 | 0.85 | HTR2A (0.51) | HTR2AHRH1CHRM1ALDH1A1KDM4E | |
| SCHEMBL9857014 | 0.84 | TAAR1 (0.54) | HTR2AHRH1CHRM1LMNATAAR1 | |
| SCHEMBL9856945 | 0.82 | HTR2A (0.49) | HTR2AHRH1CHRM1ALDH1A1UBE2N | |
| SCHEMBL9857075 | 0.82 | CALM1 (0.54) | HTR2AHRH1ALDH1A1TAAR1SLC6A2 | |
| SCHEMBL9856509 | 0.81 | HTR2A (0.51) | HTR2AHRH1KDM4ELMNASIGMAR1 | |
| SCHEMBL9856663 | 0.81 | HTR2A (0.44) | HTR2AHRH1CHRM1SIGMAR1TAAR1 | |
| SCHEMBL9857074 | 0.80 | CYSLTR2 (0.47) | HTR2AHRH1CHRM1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |