Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857027 | 0.84 | HTR2A (0.49) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL9856702 | 0.84 | TAAR1 (0.49) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL9856860 | 0.84 | HTR2A (0.49) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL9856741 | 0.84 | HTR2A (0.49) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL9857075 | 0.81 | CALM1 (0.54) | TAAR1HTR2AHRH1AOC3SLC6A2 | |
| SCHEMBL9856663 | 0.80 | HTR2A (0.44) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL9856509 | 0.80 | HTR2A (0.51) | HTR2AHRH1SLC6A4LMNACYP2D6 | |
| SCHEMBL9857074 | 0.79 | CYSLTR2 (0.47) | HTR2AHRH1SLC6A4CHRM1LMNA | |
| SCHEMBL9856945 | 0.78 | HTR2A (0.49) | TAAR1HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL9856457 | 0.78 | HTR2A (0.51) | HTR2AHRH1SLC6A2SLC6A4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |