Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473316 | 1.00 | FAAH (0.41) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9473895 | 0.88 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL9473912 | 0.88 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL9473565 | 0.85 | SCN3A (0.41) | MEN1KMT2A | |
| SCHEMBL9857009 | 0.85 | SCN3A (0.41) | FAAHMEN1KMT2A | |
| SCHEMBL9857334 | 0.85 | SCN3A (0.41) | FAAHMEN1KMT2A | |
| SCHEMBL9474084 | 0.84 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL9473162 | 0.84 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL9473272 | 0.82 | MAPT (0.45) | MEN1KMT2A | |
| SCHEMBL9856770 | 0.80 | ITGA4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437103-A2 | Substituted 5-(alkyl)carboxamide imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-17 | — | — | EP | disclosed |