SCHEMBL985723

SCHEMBL985723

CC(C)[Si](c1ccccc1)(C(C)C)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
TAAR1 Q96RJ0 4/20 0.33
SLC6A2 P23975 3/20 0.33
LMNA P02545 3/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
MAOA P21397 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
ADRA2A P08913 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP19A1 P11511 1/20 0.32
CHRM2 P08172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11056941 0.78 ESR1 (0.34) ESR1ESR2TDP1TAAR1SLC6A2
SCHEMBL9763717 0.77 ESR1 (0.37) ESR1ESR2TDP1TAAR1SLC6A2
SCHEMBL5180601 0.77 ESR1 (0.37) ESR1ESR2TDP1TAAR1SLC6A2
SCHEMBL13766348 0.77 ESR1 (0.37) ESR1ESR2TDP1TAAR1SLC6A2
SCHEMBL23557563 0.74 ESR1 (0.41) ESR1ESR2TDP1TAAR1SLC6A2
SCHEMBL14959333 0.74 ESR1 (0.41) ESR1ESR2TDP1TAAR1SLC6A2
SCHEMBL3895956 0.74 LMNA (0.38) TAAR1SLC6A2LMNASLC6A4SLC6A3
SCHEMBL14841766 0.74 ESR1 (0.37) ESR1ESR2TDP1LMNACYP2D6
SCHEMBL708624 0.72 CYP2D6 (0.34) ESR1ESR2TDP1TAAR1SLC6A2
SCHEMBL705725 0.72 ESR1 (0.34) ESR1ESR2TDP1TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9548454-B2 Method for the oriented crystallization of materials using a particle as a crystallization nucleus that has a surface partly functionalized with at least one group having an affinity for the material to be crystallized COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-01-17 US claimed
US-8952090-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-02-10 US claimed
EP-2705551-B1 METHOD FOR THE ORIENTED CRYSTALLIZATION OF MATERIALS COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-01-14 EP claimed
US-20140127855-A1 METHOD FOR THE ORIENTED CRYSTALLIZATION OF MATERIALS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-05-08 US claimed
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 WO claimed
US-9970103-B2 Film deposition material, sealing film using the same and use thereof TOSOH CORPORATION (JP) 2018-05-15 US disclosed
CN-103781937-B Filmogen, the diaphragm seal using the filmogen, and application thereof 东曹株式会社 2017-05-31 CN disclosed
US-9548454-B2 Method for the oriented crystallization of materials using a particle as a crystallization nucleus that has a surface partly functionalized with at least one group having an affinity for the material to be crystallized COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-01-17 US disclosed
US-20160326642-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2016-11-10 US disclosed
US-8952090-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-02-10 US disclosed
EP-2705551-B1 METHOD FOR THE ORIENTED CRYSTALLIZATION OF MATERIALS COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-01-14 EP disclosed
US-20140219903-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2014-08-07 US disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 WO disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed