SCHEMBL9857255

SCHEMBL9857255

COC(=O)C(C)OC(=O)c1cc(-c2nn(C)c(OC(F)F)c2Cl)c(Cl)cc1Cl

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857115 0.92 LMNA (0.35) MAPTSMN1; SMN2LMNAHPGD
SCHEMBL9857055 0.91 BAZ2B (0.33) SMN1; SMN2LMNA
SCHEMBL9856872 0.90 MAPT (0.36) MAPTNPSR1SMN1; SMN2HPGD
SCHEMBL9857284 0.85 BAZ2B (0.41) MAPTSMN1; SMN2LMNAHPGD
SCHEMBL9856747 0.84 PPOX (0.35) MAPTSMN1; SMN2LMNAHPGD
SCHEMBL8597494 0.83 HPGD (0.35) MAPTNPSR1SMN1; SMN2LMNAHPGD
SCHEMBL8183820 0.83 NTRK1 (0.30)
SCHEMBL7829990 0.83 TSHR (0.34)
SCHEMBL6433878 0.82 SMN1; SMN2 (0.33) MAPTSMN1; SMN2LMNAHPGD
SCHEMBL8598685 0.82 MAPT (0.33) MAPTNPSR1SMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443059-A1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1991-08-28 EP claimed
US-5032165-A 3-(substituted phenyl)pyrazole derivatives, salts thereof, and herbicides therefrom NIHON NOHYAKU COMPANY, LTD. (JP) 1991-07-16 US claimed
EP-0361114-A1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1990-04-04 EP claimed