SCHEMBL9856747

SCHEMBL9856747

CCOC(=O)C(C)OC(=O)c1cc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPOX P50336 2/20 0.35
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GUSB P08236 1/20 0.32
BAZ2B Q9UIF8 1/20 0.32
BAZ2A Q9UIF9 1/20 0.32
GAA P10253 1/20 0.31
NTRK1 P04629 7/20 0.31
TEAD2 Q15562 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857055 0.93 BAZ2B (0.33) PPOXLMNASMN1; SMN2BAZ2BBAZ2A
SCHEMBL9857115 0.92 LMNA (0.35) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL9856794 0.91 BAZ2B (0.40) LMNAMAPTHPGDSMN1; SMN2GUSB
SCHEMBL6433878 0.88 SMN1; SMN2 (0.33) LMNAMAPTHPGDSMN1; SMN2GAA
SCHEMBL9738493 0.86 GAA (0.39) PPOXLMNAMAPTHPGDSMN1; SMN2
SCHEMBL6295364 0.86 PPOX (0.46) PPOXLMNAMAPTHPGDSMN1; SMN2
SCHEMBL9857255 0.84 MAPT (0.31) LMNAMAPTHPGDSMN1; SMN2
SCHEMBL9856930 0.83 GAA (0.35) LMNAMAPTHPGDSMN1; SMN2GUSB
SCHEMBL27469166 0.83 PPOX (0.32) PPOXLMNASMN1; SMN2
SCHEMBL9857284 0.83 BAZ2B (0.41) LMNAMAPTHPGDSMN1; SMN2BAZ2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443059-A1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1991-08-28 EP claimed
US-5032165-A 3-(substituted phenyl)pyrazole derivatives, salts thereof, and herbicides therefrom NIHON NOHYAKU COMPANY, LTD. (JP) 1991-07-16 US claimed
EP-0361114-A1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1990-04-04 EP claimed
US-5015674-A Polysiloxanes for sealing semiconductors, modified with acrylates MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-14 US disclosed