Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856532 | 0.94 | SLC6A4 (0.58) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9857132 | 0.93 | SLC6A4 (0.59) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| SCHEMBL9857370 | 0.87 | SLC6A9 (0.45) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| SCHEMBL9857406 | 0.85 | CYP2D6 (0.52) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| SCHEMBL8384207 | 0.85 | HTR2A (0.60) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| SCHEMBL9856914 | 0.81 | HTR2A (0.49) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| SCHEMBL4811791 | 0.80 | HTR2A (0.70) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29009216 | 0.79 | HTR2A (0.68) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| SCHEMBL9856873 | 0.79 | SLC6A4 (0.50) | SLC6A4CYP2D6SLC6A2MEN1KMT2A | |
| SCHEMBL9857051 | 0.78 | ALDH1A1 (0.69) | SLC6A4CYP2D6SLC6A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |