Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857481 | 0.83 | F2 (0.38) | KMT2AMAPTHPGDRAB9ATSHR | |
| SCHEMBL10779090 | 0.81 | TSHR (0.39) | HSD11B1KMT2ANPSR1TSHRALDH1A1 | |
| SCHEMBL9347640 | 0.81 | TSHR (0.44) | HSD11B1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL12787299 | 0.78 | TSHR (0.38) | HSD11B1KMT2ATSHRALDH1A1F2 | |
| SCHEMBL23529640 | 0.78 | TSHR (0.41) | HSD11B1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2915807 | 0.78 | TSHR (0.41) | HSD11B1KMT2ATSHRALDH1A1F2 | |
| SCHEMBL2915808 | 0.78 | TSHR (0.41) | HSD11B1KMT2ATSHRALDH1A1F2 | |
| SCHEMBL29772371 | 0.78 | TSHR (0.41) | HSD11B1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9857471 | 0.78 | PPID (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2F2 | |
| SCHEMBL9730290 | 0.77 | TSHR (0.38) | HSD11B1KMT2AMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436851-A1 | Compounds active as inhibitors of the enzyme HMG-CoA reductase and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1991-07-17 | — | — | EP | disclosed |