Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857290 | 0.90 | POLB (0.43) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL9857292 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL8922256 | 0.81 | HSD17B10 (0.49) | ALDH1A1HSD17B10HPGDALOX15EPHX1 | |
| SCHEMBL9857856 | 0.73 | ALDH1A1 (0.60) | ALDH1A1HSD17B10HPGDALOX15EPHX1 | |
| SCHEMBL9858064 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HSD17B10HPGDALOX15EPHX1 | |
| SCHEMBL8922352 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL8920356 | 0.70 | AKR1C3 (0.40) | ALDH1A1HSD17B10HPGDALOX15MAPT | |
| SCHEMBL8923602 | 0.70 | PIK3CA (0.42) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL8541928 | 0.70 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDALOX15EPHX1 | |
| SCHEMBL27395864 | 0.68 | ALDH1A1 (0.79) | ALDH1A1HSD17B10HPGDALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431371-A1 | 3-Aminopyrroles, process for this preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-06-12 | — | — | EP | claimed |