Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857777 | 0.90 | ALDH1A1 (0.47) | POLBALDH1A1HPGDUSP2CHRNA7 | |
| SCHEMBL8922352 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HPGDUSP2FKBP1ACHRNA7 | |
| SCHEMBL9857292 | 0.72 | ALDH1A1 (0.44) | POLBALDH1A1HPGDCYP2C19CYP1A2 | |
| SCHEMBL8922256 | 0.71 | HSD17B10 (0.49) | ALDH1A1HPGDUSP2CHRNA7CYP2C9 | |
| SCHEMBL8920356 | 0.71 | AKR1C3 (0.40) | POLBALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL8923602 | 0.71 | PIK3CA (0.42) | ALDH1A1RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL9857773 | 0.70 | ALDH1A1 (0.52) | POLBALDH1A1HPGDUSP2FKBP1A | |
| SCHEMBL8923375 | 0.69 | ALDH1A1 (0.63) | ALDH1A1HPGDUSP2FKBP1ACHRNA7 | |
| SCHEMBL8923442 | 0.65 | ALDH1A1 (0.83) | ALDH1A1HPGDUSP2FKBP1AALOX15 | |
| SCHEMBL9858064 | 0.65 | ALDH1A1 (0.57) | POLBALDH1A1HPGDUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431371-A1 | 3-Aminopyrroles, process for this preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-06-12 | — | — | EP | claimed |