Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287040 | 0.78 | — | — | |
| Ethane SCHEMBL4627940 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2CRBN | |
| SCHEMBL9857714 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL919138 | 0.71 | SMN1; SMN2 (0.60) | SMN1; SMN2 | |
| SCHEMBL1603875 | 0.71 | — | — | |
| SCHEMBL9857770 | 0.69 | CTRB1 (0.54) | — | |
| SCHEMBL19285856 | 0.68 | — | — | |
| SCHEMBL12595244 | 0.68 | — | — | |
| SCHEMBL14648600 | 0.67 | CRBN (0.40) | SMN1; SMN2CRBN | |
| SCHEMBL10951855 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072023-A | Reacting lactone with ester anion to form cyclohexenone ester; oxidizing or dehydrogenating the intermediate | E. R. SQUIBB & SONS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0442495-A1 | Process for preparing highly substituted phenyls | E.R. SQUIBB & SONS, INC. (US) | 1991-08-21 | — | — | EP | disclosed |