Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15187638 | 0.81 | ALDH1A1 (0.37) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL9857879 | 0.74 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL18193405 | 0.72 | PLAU (0.34) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL1603875 | 0.67 | — | — | |
| SCHEMBL9857770 | 0.65 | CTRB1 (0.54) | MEN1ALDH1A1MAPTPKMKMT2A | |
| SCHEMBL9881071 | 0.64 | HTT (0.34) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL2691341 | 0.64 | — | — | |
| SCHEMBL10951855 | 0.63 | — | — | |
| SCHEMBL919138 | 0.63 | SMN1; SMN2 (0.60) | KDM4EPOLBMAPT | |
| SCHEMBL11580763 | 0.60 | MAPT (0.34) | KDM4EMEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072023-A | Reacting lactone with ester anion to form cyclohexenone ester; oxidizing or dehydrogenating the intermediate | E. R. SQUIBB & SONS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0442495-A1 | Process for preparing highly substituted phenyls | E.R. SQUIBB & SONS, INC. (US) | 1991-08-21 | — | — | EP | disclosed |