SCHEMBL985817

SCHEMBL985817

COc1cc(C(=O)O)cc(Cl)c1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.75
CA1 P00915 2/20 0.75
CA2 P00918 2/20 0.75
CA4 P22748 2/20 0.75
CA6 P23280 2/20 0.75
CA7 P43166 2/20 0.75
CA9 Q16790 2/20 0.75
CA14 Q9ULX7 2/20 0.75
CA3 P07451 1/20 0.75
PKM P14618 1/20 0.75
CA5A P35218 1/20 0.75
CA5B Q9Y2D0 1/20 0.75
PTGS2 P35354 1/20 0.70
TTR P02766 2/20 0.64
TPMT P51580 3/20 0.59
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
HSD17B10 Q99714 1/20 0.55
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Syringic Acid SCHEMBL42751 0.86 CA12 (1.00) CA12CA1CA2CA4CA6
Syringic Acid SCHEMBL27602358 0.86 CA12 (1.00) CA12CA1CA2CA4CA6
SCHEMBL31346673 0.85 LMNA (0.75) CA12CA1CA2CA4CA6
SCHEMBL4898203 0.85 MEN1 (0.55) CA12CA1CA2CA4CA6
Syringic Acid SCHEMBL27832093 0.84 PKM (0.96) CA12CA1CA2CA4CA6
Syringic Acid SCHEMBL30250854 0.84 PKM (0.96) CA12CA1CA2CA4CA6
SCHEMBL1586741 0.84 KMT2A (0.54) CA12CA1CA2CA4CA6
SCHEMBL4907208 0.83 CA12 (0.60) CA12CA1CA2CA4CA6
SCHEMBL30615314 0.82 PTGS2 (1.00) CA12CA1CA2CA4CA6
SCHEMBL975675 0.82 PTGS2 (1.00) CA12CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120109344-B Process for extracting waste lithium ion battery by deep eutectic solvent 江西申德机械科技有限公司 2025-09-05 CN disclosed
CN-120109344-A Process for extracting waste lithium ion battery by deep eutectic solvent 江西申德机械科技有限公司 2025-06-06 CN disclosed
US-9873661-B2 Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors NEW YORK UNIVERSITY (US) 2018-01-23 US disclosed
US-9873661-B2 Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors NEW YORK UNIVERSITY (US) 2018-01-23 US disclosed
EP-2444120-B1 Spirocyclic amiloride analogues as ENac blockers NOVARTIS AG (CH) 2017-09-27 EP disclosed
US-9643983-B2 Treating diseases mediated by blockade of the epithelial sodium channel with pyrazine-2-carboxamide derivatives NOVARTIS AG (CH) 2017-05-09 US disclosed
US-20170100317-A1 COMPOSITION COMPRISING A PARTICULAR PHENOLIC COUPLER AND AN OXIDATION BASE L'OREAL (FR) 2017-04-13 US disclosed
US-20170100317-A1 COMPOSITION COMPRISING A PARTICULAR PHENOLIC COUPLER AND AN OXIDATION BASE L'OREAL (FR) 2017-04-13 US disclosed
US-9447028-B2 Therapeutic aryl-amido-aryl compounds and their use KING'S COLLEGE LONDON (GB) 2016-09-20 US disclosed
US-9447028-B2 Therapeutic aryl-amido-aryl compounds and their use KING'S COLLEGE LONDON (GB) 2016-09-20 US disclosed
EP-1326853-B1 THIADIAZOLES AND OXADIAZOLES AND THEIR USE AS PHOSPHODIESTERASE-7 INHIBITORS WARNER LAMBERT CO (US) 2005-09-07 EP disclosed
CN-1599728-A Sulfamate-containing 1,2, 4-triazole derivatives as aromatase inhibitors STERIX LTD (GB) 2005-03-23 CN disclosed
EP-1446388-A1 1,2,4-TRIAZOLE DERIVATIVES CONTAINING A SULPHAMATE GROUP AS AROMATASE INHIBITORS Sterix Limited (GB) 2004-08-18 EP disclosed
US-20040019016-A1 Polycyclic compounds containing a central trivalent atom to which is attached either direct or indirectly via a linker a two or three ring system and a ring system contining sulphamate group as substituent; steroid sulfatase inhibitor RICHTER GEDEON NYRT. (HU) 2004-01-29 US disclosed
EP-1326853-A1 NEW THIADIAZOLES AND OXADIAZOLES AND THEIR USE AS PHOSPHODIESTERASE-7 INHIBITORS Warner-Lambert Company LLC (US) 2003-07-16 EP disclosed
WO-2003045925-A1 1,2,4-TRIAZOLE DERIVATIVES CONTAINING A SULPHAMATE GROUP AS AROMATASE INHIBITORS STERIX LIMITED (GB) 2003-06-05 WO disclosed
US-20030045557-A1 Thiadiazoles and oxadiazoles and their use as phosphodiesterase-7 inhibitors WARNER-LAMBERT COMPANY 2003-03-06 US disclosed
WO-2002028847-A1 NEW THIADIAZOLES AND OXADIAZOLES AND THEIR USE AS PHOSPHODIESTERASE-7 INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2002-04-11 WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170100317-A1 COMPOSITION COMPRISING A PARTICULAR PHENOLIC COUPLER AND AN OXIDATION BASE CBR3, KRT18, CBR1 CA12 1016/4885CA1 896/4885CA2 983/4885
US-20030045557-A1 Thiadiazoles and oxadiazoles and their use as phosphodiesterase-7 inhibitors PDE3A, PDE3B, PDE7A CA12 4844/4885CA1 4734/4885CA2 2400/4885
US-20040019016-A1 Polycyclic compounds containing a central trivalent atom to which is attached either direct or indirectly via a linker a two or three ring system and a ring system contining sulphamate group as substituent; steroid sulfatase inhibitor STS, CYP21A2, SULT1E1 CA12 215/4885CA1 124/4885CA2 375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.