Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28793487 | 0.84 | ALDH1A1 (0.54) | ALDH1A1ALOX15AKT1LMNAMEN1 | |
| SCHEMBL6693580 | 0.84 | CES2 (0.44) | ALDH1A1CYP3A4ALOX15BCHEGUSB | |
| SCHEMBL38132 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP3A4ALOX15BCHEGUSB | |
| SCHEMBL5369812 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15BCHEGUSB | |
| Benzene SCHEMBL28254104 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ALOX15AKT1LMNATDP1 | |
| SCHEMBL30259301 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ALOX15AKT1LMNATDP1 | |
| SCHEMBL31100 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ALOX15AKT1LMNATDP1 | |
| Bicarbonate SCHEMBL15861641 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ALOX15AKT1GSRLMNA | |
| SCHEMBL2536413 | 0.80 | AKT1 (0.50) | ALDH1A1CYP3A4ALOX15BCHEGUSB | |
| SCHEMBL2856375 | 0.80 | ALDH1A1 (0.54) | ALDH1A1ALOX15AKT1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747734-B1 | Contact lenses with hydrophilic crosslinkers | JOHNSON & JOHNSON VISION PROD (US) | 2001-08-22 | — | — | EP | claimed |
| US-5654350-A | POLYMERIZATION OF MONOMER MIXTURE CONTAINING A CARBOXYL FUNCTIONAL CURING AGENT HAVING UNSATURATED END GROUPS AND ESTER AND/OR ETHER GROUPS | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1997-08-05 | — | — | US | claimed |
| EP-0747734-A2 | Contact lenses with hydrophilic crosslinkers | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-12-11 | — | — | EP | claimed |
| US-5565539-A | UNSATURATED ESTER CROSSLINKING AGENT; IMPROVED OXYGEN TRANSMISSIVITY | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-10-15 | — | — | US | claimed |
| US-5563183-A | DIFFUSION OF WATER AND OXYGEN | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-10-08 | — | — | US | claimed |
| JP-9143230-A | — | — | None | — | — | JP | disclosed |
| WO-2024070641-A1 | OPTICAL FILM, POLARIZING PLATE, COMPOSITION FOR ALIGNMENT FILM FORMATION, AND METHOD FOR PRODUCING POLARIZING PLATE | 富士フイルム株式会社 | 2024-04-04 | — | — | WO | disclosed |
| WO-2024070633-A1 | OPTICAL FILM, POLARIZING PLATE, COMPOSITION FOR FORMING ALIGNMENT FILM, AND METHOD FOR PRODUCING POLARIZING PLATE | 富士フイルム株式会社 | 2024-04-04 | — | — | WO | disclosed |
| US-8025936-B2 | Optical compensation film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-09-27 | — | — | US | disclosed |
| US-7875325-B2 | comprising a transparent film, and, on the film, at least one layer formed by applying a composition comprising a zirconium compound, a vinyl alcohol-based resin, and an aminocarboxylic acid or its derivative to a surface | FUJIFILM CORPORATION (JP) | 2011-01-25 | — | — | US | disclosed |
| US-20090091690-A1 | Optical Compensation Film, Polarizing Plate and Liquid Crystal Display Device | FUJIFILM CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20090086130-A1 | OPTICAL FILM, POLARIZING PLATE, AND LIQUID-CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| JP-H09143230-A | CONTACT LENS CONTAINING HYDROPHILIC CROSS-LINKING AGENT AND ITS PRODUCTION | JOHNSON & JOHNSON VISION PROD INC | 1997-06-03 | — | — | JP | disclosed |
| EP-0747734-A2 | Contact lenses with hydrophilic crosslinkers | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5565539-A | UNSATURATED ESTER CROSSLINKING AGENT; IMPROVED OXYGEN TRANSMISSIVITY | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5565539-A | UNSATURATED ESTER CROSSLINKING AGENT; IMPROVED OXYGEN TRANSMISSIVITY | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5563183-A | DIFFUSION OF WATER AND OXYGEN | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5563183-A | DIFFUSION OF WATER AND OXYGEN | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0726486-A2 | Optical compensatory sheet | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-4855282-A | Recording material and method for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090086130-A1 | OPTICAL FILM, POLARIZING PLATE, AND LIQUID-CRYSTAL DISPLAY DEVICE | ZKSCAN2, VCL, ZRANB2 | ALDH1A1 2609/4885CYP3A4 2806/4885ALOX15 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.