SCHEMBL6693580

SCHEMBL6693580

C=Cc1ccccc1C(=O)C(=O)c1ccccc1C=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.44
CES1 P23141 4/20 0.44
ALDH1A1 P00352 4/20 0.44
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.40
BCHE P06276 2/20 0.38
GUSB P08236 1/20 0.38
AKT1 P31749 1/20 0.38
GSR P00390 1/20 0.37
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SRC P12931 1/20 0.36
CYP2C19 P33261 1/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065186 0.90 CES2 (0.54) CES2CES1CYP3A4AKT1LMNA
Water SCHEMBL6094264 0.88 CES2 (0.52) CES2CES1CYP3A4AKT1LMNA
Ammonia Solution, Strong SCHEMBL4936520 0.88 CES2 (0.52) CES2CES1CYP3A4AKT1LMNA
SCHEMBL38132 0.86 ALDH1A1 (0.44) CES2CES1ALDH1A1CYP3A4ALOX15
SCHEMBL10478995 0.86 HPGD (0.39) CES2CES1ALDH1A1CYP3A4ALOX15
SCHEMBL985923 0.84 ALDH1A1 (0.43) CES2CES1ALDH1A1CYP3A4ALOX15
SCHEMBL30259301 0.84 ALDH1A1 (0.56) ALDH1A1ALOX15AKT1LMNATDP1
SCHEMBL31100 0.84 ALDH1A1 (0.56) ALDH1A1ALOX15AKT1LMNATDP1
Trimethylammonium SCHEMBL598821 0.82 RAB9A (0.46) CES2CES1CYP3A4AKT1LMNA
Trimethylammonium SCHEMBL597991 0.82 RAB9A (0.46) CES2CES1CYP3A4AKT1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1429703-A2 ABSORBENT STRUCTURE ABSORBENT ARTICLE WATER ABSORBENT RESIN AND ITS PRODUCTION PROCESS AND EVALUATION METHOD Nippon Shokubai Co., Ltd. (JP) 2004-06-23 EP disclosed
US-20040019342-A1 Absorbent structure, absorbent article, water-absorbent resin, and its production process and evaluation method NIPPON SHOKUBAI CO., LTD. (JP) 2004-01-29 US disclosed
WO-2003026707-A2 ABSORBENT STRUCTURE, ABSORBENT ARTICLE, WATER-ABSORBENT RESIN, AND ITS PRODUCTION PROCESS AND EVALUATION METHOD NIPPON SHOKUBAI CO., LTD. (JP) 2003-04-03 WO disclosed