SCHEMBL985942

SCHEMBL985942

OC1(O)c2ccccc2-c2ccc(-c3ccccc3)c(-c3ccccc3)c21

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PDK2 Q15119 13/20 0.41
HNF4A P41235 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
SLC6A3 Q01959 2/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30741411 0.85 THRB (0.50) THRBTDP1PDK2HNF4AALDH1A1
SCHEMBL3401845 0.85 THRB (0.50) THRBTDP1PDK2HNF4AALDH1A1
SCHEMBL29850254 0.81 THRB (0.38) THRBTDP1PDK2HNF4AALDH1A1
SCHEMBL258798 0.79 ALDH1A1 (0.36) THRBTDP1PDK2HNF4AALDH1A1
SCHEMBL29589837 0.79 ALDH1A1 (0.36) THRBTDP1PDK2HNF4AALDH1A1
SCHEMBL258717 0.77 MEN1 (0.42) THRBTDP1PDK2HNF4AALDH1A1
Ammonia Solution, Strong SCHEMBL3793717 0.77 ALDH1A1 (0.35) THRBTDP1PDK2HNF4AALDH1A1
Ammonia Solution, Strong SCHEMBL27767041 0.76 MEN1 (0.41) THRBTDP1PDK2HNF4AALDH1A1
SCHEMBL14739125 0.74 MEN1 (0.40) TDP1PDK2HNF4AALDH1A1BCL2L1
Ammonia Solution, Strong SCHEMBL27746262 0.73 APEX1 (0.36) THRBTDP1PDK2HNF4ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1597303-B1 METHOD OF MAKING BRANCHED POLYPHOSPHONATES FRX POLYMERS INC (US) 2012-11-07 EP claimed
EP-2275473-A1 Branched Polyphosphonates FRX Polymers LLC (US) 2011-01-19 EP claimed
CN-1777632-B Branched polyphosphonates FRX POLYMERS INC 2011-01-12 CN claimed
US-7816486-B2 Branched polyphosphonates FRX POLYMERS, INC. (US) 2010-10-19 US claimed
US-20070032633-A1 Branched polyphosphonates TRITON SYSTEMS, INC. (US) 2007-02-08 US claimed
JP-2006518804-A 2006-08-17 JP claimed
CN-1777632-A Branched polyphosphonates TRITON SYSTEMS INC (US) 2006-05-24 CN claimed
EP-1597303-A1 BRANCHED POLYPHOSPHONATES Triton Systems Inc. (US) 2005-11-23 EP claimed
WO-2004076536-A1 BRANCHED POLYPHOSPHONATES TRITON SYSTEMS INC. (US) 2004-09-10 WO claimed
US-10167377-B2 Phosphorus containing epoxy compounds and compositions therefrom FRX POLYMERS, INC. (US) 2019-01-01 US disclosed
US-20180016412-A1 FLAME RETARDANT COMBINATIONS FOR POLYESTERS AND FLAME RETARDED POLYESTER MOULDING COMPOSITIONS THEREFROM CLARIANT INT LTD (CH) 2018-01-18 US disclosed
CN-106674914-A Flame retardant combinations for polyester elastomers and flame retarded extrusion or molding compositions therefrom 科莱恩金融(BVI)有限公司 2017-05-17 CN disclosed
EP-2948464-A1 PHOSPHORUS CONTAINING EPOXY COMPOUNDS AND COMPOSITIONS THEREFROM FRX Polymers, Inc. (US) 2015-12-02 EP disclosed
WO-2014116669-A1 PHOSPHORUS CONTAINING EPOXY COMPOUNDS AND COMPOSITIONS THEREFROM FRX POLYMERS, INC. (US) 2014-07-31 WO disclosed
US-20070129511-A1 Poly(Block-Phosphonato-Ester) And Poly(Block-Phosphonato-Carbonate) And Methods of Making Same FRX POLYMERS, INC. 2007-06-07 US disclosed
WO-2007022008-A2 POLY (BLOCK-PHOSPHONATO-ESTER) AND POLY (BLOCK-PHOSPHONATO-CARBONATE) AND METHODS OF MAKING SAME FRX POLYMERS, LLP (US) 2007-02-22 WO disclosed
US-20070032633-A1 Branched polyphosphonates TRITON SYSTEMS, INC. (US) 2007-02-08 US disclosed
CN-1777632-A Branched polyphosphonates TRITON SYSTEMS INC (US) 2006-05-24 CN disclosed
EP-1597303-A1 BRANCHED POLYPHOSPHONATES Triton Systems Inc. (US) 2005-11-23 EP disclosed
WO-2004076536-A1 BRANCHED POLYPHOSPHONATES TRITON SYSTEMS INC. (US) 2004-09-10 WO disclosed