SCHEMBL3401845

SCHEMBL3401845

OC1(O)c2ccccc2-c2cccc(-c3ccccc3)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PDK2 Q15119 8/20 0.42
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
BACE1 P56817 2/20 0.38
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
HNF4A P41235 1/20 0.37
MAPK1 P28482 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
CASP1 P29466 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30741411 1.00 THRB (0.50) THRBTDP1PDK2ALDH1A1HSD17B10
SCHEMBL985942 0.85 THRB (0.44) THRBTDP1PDK2ALDH1A1HSD17B10
SCHEMBL27846553 0.85 PDK2 (0.49) THRBTDP1PDK2ALDH1A1HSD17B10
SCHEMBL27643267 0.79 THRB (0.46) THRBTDP1PDK2ALDH1A1HSD17B10
SCHEMBL27497315 0.79 THRB (0.71) THRBTDP1PDK2ALDH1A1HSD17B10
SCHEMBL25818400 0.78 THRB (0.43) THRBTDP1PDK2ALDH1A1HSD17B10
SCHEMBL30899336 0.77 PDK2 (0.56) THRBTDP1PDK2ALDH1A1BACE1
SCHEMBL4325901 0.77 PDK2 (0.56) THRBTDP1PDK2ALDH1A1BACE1
SCHEMBL26658376 0.76 SLC6A3 (0.40) THRBTDP1PDK2ALDH1A1HSD17B10
SCHEMBL29536234 0.76 SLC6A3 (0.40) THRBTDP1PDK2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068268-A Nautical coatings SHELL OIL COMPANY (US) 1991-11-26 US claimed
US-12535736-B2 Anti-reflective hard mask composition CHEMPOLE CO., LTD. (KR) 2026-01-27 US disclosed
CN-111458981-B Hard mask composition for anti-reflection OLAS有限公司 2024-02-02 CN disclosed
US-20230375929-A1 Anti-reflective hard mask composition CHEMPOLE CO., LTD. (KR) 2023-11-23 US disclosed
WO-2022092394-A1 ANTI-REFLECTIVE HARD MASK COMPOSITION 최상준 2022-05-05 WO disclosed
CN-111458981-A Antireflective hardmask composition OLAS有限公司 2020-07-28 CN disclosed
US-10189947-B2 Composition of anti-reflective hardmask CHOI SANG JUN (KR) 2019-01-29 US disclosed
CN-104861171-B Insoluble and branched polyphosphonates and its correlation technique FRX聚合物股份有限公司 2018-04-24 CN disclosed
US-9745424-B2 Insoluble and branched polyphosphonates and methods related thereto FRX POLYMERS, INC. (US) 2017-08-29 US disclosed
US-20170198096-A1 Composition of Anti-Reflective Hardmask CHOI SANG JUN (KR) 2017-07-13 US disclosed
US-6861499-B2 Branched polyphosphonates that exhibit an advantageous combination of properties, and methods related thereto TRITON SYSTEMS, INC. (US) 2005-03-01 US disclosed
US-20040167284-A1 Branched polyphosphonates that exhibit an advantageous combination of properties, and methods related thereto FRX POLYMERS, INC. 2004-08-26 US disclosed
US-20040167283-A1 Linear polyphosphonates that exhibit an advantageous combination of properties, and methods related thereto TRITON SYSTEM, INC. 2004-08-26 US disclosed
JP-2003165835-A POLYCARBONATE RESIN TEIJIN CHEM LTD 2003-06-10 JP disclosed
EP-0854891-B1 PROCESS FOR PREPARING COATED PLASTIC SURFACES DOW GLOBAL TECHNOLOGIES INC (US) 2003-05-28 EP disclosed
JP-2002080734-A METHOD FOR PRODUCING POLYMER TEIJIN CHEM LTD 2002-03-19 JP disclosed
JP-2002080580-A METHOD FOR MANUFACTURING POLYMER TEIJIN CHEM LTD 2002-03-19 JP disclosed
EP-0854891-A1 COATED PLASTIC SUBSTRATE THE DOW CHEMICAL COMPANY (US) 1998-07-29 EP disclosed
US-5718967-A PLASMA POLYMERIZED ORGANOSILICON COMPOUNDS; LIQUID CRYSTAL DISPLAY DEVICES THE DOW CHEMICAL COMPANY (US) 1998-02-17 US disclosed
WO-1997013802-A1 COATED PLASTIC SUBSTRATE THE DOW CHEMICAL COMPANY (US) 1997-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12535736-B2 Anti-reflective hard mask composition CDH1, MYB, YWHAZ THRB 3433/4885TDP1 2780/4885PDK2 4257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.