SCHEMBL985997

SCHEMBL985997

CC(C)C[C@H](N)C(=O)NC(=O)c1ccc2ccccc2c1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 2/20 0.58
METAP2 P50579 4/20 0.52
METAP1 P53582 2/20 0.48
CCR1 P32246 1/20 0.47
HDAC3 O15379 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
CTSK P43235 4/20 0.47
ADAM17 P78536 1/20 0.46
CASP1 P29466 1/20 0.46
CASP3 P42574 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8669233 0.99 LARS1 (0.57) LARS1METAP2METAP1CCR1HDAC3
SCHEMBL10439613 0.88 LARS1 (0.52) LARS1METAP2METAP1CCR1HDAC3
SCHEMBL9390095 0.85 METAP2 (0.49) METAP2HDAC3HDAC1HDAC2CASP1
SCHEMBL4267098 0.84 METAP2 (0.51) METAP2METAP1HDAC3HDAC1HDAC2
SCHEMBL17822181 0.83 LARS1 (0.56) LARS1CTSK
SCHEMBL7298409 0.83 LARS1 (0.56) LARS1CTSK
SCHEMBL2545018 0.82 METAP2 (0.49) METAP2METAP1HDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL10520625 0.81 LARS1 (0.55) LARS1CTSK
SCHEMBL6828289 0.81 NAMPT (0.57) METAP2CCR1NPC1RAB9A
SCHEMBL21753951 0.80 METAP2 (0.47) METAP2METAP1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 EP claimed
US-9701968-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2017-07-11 US claimed
US-20160312263-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2016-10-27 US claimed
WO-2016060714-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2016-04-21 WO claimed
US-20160102335-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY 2016-04-14 US claimed
US-8507248-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-08-13 US claimed
US-8173389-B2 Process for determining the effectiveness of a sterilization AMERICAN STERILIZER COMPANY (US) 2012-05-08 US claimed
US-20100267044-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR FRANCISKOVICH PHILLIP P 2010-10-21 US claimed
EP-2084294-A2 STERILIZATION INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
US-20090117603-A1 STERILIZATION INDICATOR FRANCISKOVICH PHILLIP P 2009-05-07 US claimed
WO-2008082728-A2 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-10 WO claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO claimed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-20080070272-A1 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-6623955-B2 Exposing source of active enzyme to sterilization cycle, contacting enzyme after cycle with aqueous buffer and substrate specific for and reactive with active enzyme to form enzyme modified product, detecting viable microorganisms 3M INNOVATIVE PROPERTIES COMPANY 2003-09-23 US claimed
US-20260137736-A1 PROBIOTIC LACTOBACILLUS STRAIN COMPOSITIONS AND APPLICATIONS THEREFOR INCLUDING FOR LEAKY GUT AND INFLAMMATION BIOMEDIT LLC (US) 2026-05-21 US disclosed
US-12564613-B2 Strains having effects of preventing or treating cancers GENOME AND COMPANY (KR) 2026-03-03 US disclosed
US-4546077-A Leucine dehydrogenase and a process for production thereof UNITIKA LTD. (JP) 1985-10-08 US disclosed
US-4209459-A USEFUL FOR ASSAY OF LEUCIN-AMINOPEPTIDASE ACTIVITY NITTO BOSEKI CO., LTD. (JP) 1980-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137736-A1 PROBIOTIC LACTOBACILLUS STRAIN COMPOSITIONS AND APPLICATIONS THEREFOR INCLUDING FOR LEAKY GUT AND INFLAMMATION FABP2, SLC10A2, ALPI LARS1 434/4885METAP2 1827/4885METAP1 1314/4885
US-12564613-B2 Strains having effects of preventing or treating cancers PDCD1, TOP1, CD274 LARS1 150/4885METAP2 4215/4885METAP1 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.