SCHEMBL2545018

SCHEMBL2545018

CC(C)[C@H](N)C(=O)NC(=O)c1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ METAP2 P50579 5/20 0.49
▸ METAP1 P53582 2/20 0.48
▸ NPC1 O15118 5/20 0.48
▸ RAB9A P51151 5/20 0.48
▸ HDAC3 O15379 2/20 0.47
▸ HDAC1 Q13547 2/20 0.47
▸ HDAC2 Q92769 2/20 0.47
▸ CES2 O00748 1/20 0.46
▸ CES1 P23141 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ CASP3 P42574 1/20 0.46
▸ SENP7 Q9BQF6 1/20 0.46
▸ DEGS1 O15121 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4267098 0.88 METAP2 (0.51) METAP2METAP1NPC1RAB9AHDAC3
Cystine SCHEMBL9132888 0.87 METAP2 (0.47) METAP2METAP1NPC1RAB9AHDAC3
Bromide SCHEMBL4657453 0.85 HDAC3 (0.48) METAP2METAP1NPC1RAB9AHDAC3
SCHEMBL7043430 0.82 METAP2 (0.46) METAP2METAP1NPC1RAB9AHDAC3
SCHEMBL985997 0.82 LARS1 (0.58) METAP2METAP1NPC1RAB9AHDAC3
SCHEMBL7700177 0.81 ALDH1A1 (0.50) NPC1RAB9AHDAC3HDAC1HDAC2
Hydrochloric Acid SCHEMBL8669233 0.81 LARS1 (0.57) METAP2METAP1NPC1RAB9AHDAC3
SCHEMBL10635436 0.78 FURIN (0.45) KMT2A
SCHEMBL11010750 0.78 PKM (0.45) MEN1KMT2A
SCHEMBL9390095 0.77 METAP2 (0.49) METAP2NPC1RAB9AHDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 — — EP claimed
US-9701968-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2017-07-11 — — US claimed
US-20160312263-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2016-10-27 — — US claimed
WO-2016060714-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2016-04-21 — — WO claimed
US-20160102335-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY 2016-04-14 — — US claimed
US-8507248-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-08-13 — — US claimed
US-8173389-B2 Process for determining the effectiveness of a sterilization AMERICAN STERILIZER COMPANY (US) 2012-05-08 — — US claimed
US-20100267044-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR FRANCISKOVICH PHILLIP P 2010-10-21 — — US claimed
EP-2084294-A2 STERILIZATION INDICATOR American Sterilizer Company (US) 2009-08-05 — — EP claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 — — EP claimed
US-20090117603-A1 STERILIZATION INDICATOR FRANCISKOVICH PHILLIP P 2009-05-07 — — US claimed
WO-2008082728-A2 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-10 — — WO claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 — — WO claimed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 — — US claimed
US-20080070272-A1 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY 2008-03-20 — — US claimed
US-6623955-B2 Exposing source of active enzyme to sterilization cycle, contacting enzyme after cycle with aqueous buffer and substrate specific for and reactive with active enzyme to form enzyme modified product, detecting viable microorganisms 3M INNOVATIVE PROPERTIES COMPANY 2003-09-23 — — US claimed
US-20260137736-A1 PROBIOTIC LACTOBACILLUS STRAIN COMPOSITIONS AND APPLICATIONS THEREFOR INCLUDING FOR LEAKY GUT AND INFLAMMATION BIOMEDIT LLC (US) 2026-05-21 — — US disclosed
US-12564613-B2 Strains having effects of preventing or treating cancers GENOME AND COMPANY (KR) 2026-03-03 — — US disclosed
EP-0361977-A2 Peptides having T cell suppressor activity IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1990-04-04 — — EP disclosed
CN-87103752-A Prepare a kind of monadic method for compositions that suppresses or eliminate — 1988-09-21 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137736-A1 PROBIOTIC LACTOBACILLUS STRAIN COMPOSITIONS AND APPLICATIONS THEREFOR INCLUDING FOR LEAKY GUT AND INFLAMMATION FABP2, SLC10A2, ALPI METAP2 1827/4885METAP1 1314/4885NPC1 2028/4885
US-12564613-B2 Strains having effects of preventing or treating cancers PDCD1, TOP1, CD274 METAP2 4215/4885METAP1 2212/4885NPC1 3432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback