Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043430 | 0.90 | METAP2 (0.46) | METAP2NPC1RAB9AMETAP1HDAC3 | |
| SCHEMBL2545018 | 0.88 | METAP2 (0.49) | METAP2NPC1RAB9AMETAP1HDAC3 | |
| SCHEMBL985997 | 0.84 | LARS1 (0.58) | METAP2NPC1RAB9AMETAP1HDAC3 | |
| Hydrochloric Acid SCHEMBL8669233 | 0.83 | LARS1 (0.57) | METAP2NPC1RAB9AMETAP1HDAC3 | |
| SCHEMBL6888897 | 0.83 | CCR1 (0.49) | METAP2 | |
| Bromide SCHEMBL4657453 | 0.82 | HDAC3 (0.48) | METAP2NPC1RAB9AMETAP1HDAC3 | |
| SCHEMBL12259734 | 0.80 | ALDH1A1 (0.53) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL9390095 | 0.80 | METAP2 (0.49) | METAP2NPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL6828289 | 0.79 | NAMPT (0.57) | METAP2NPC1RAB9ATDP1 | |
| SCHEMBL9731103 | 0.78 | PLAU (0.58) | NPC1RAB9AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2866900-A2 | SOOTHING TOPICAL COMPOSITION CONTAINING PAEONIA AND NYMPHAEA EXTRACTS | Société De Recherche Cosmétique S.à.r.L. (LU) | 2015-05-06 | — | — | EP | disclosed |
| US-20140045205-A1 | GLUTAMYL AMINOPEPTIDASE AS A MARKER OF RENAL DAMAGE | UNIVERSIDAD DE GRANADA (ES) | 2014-02-13 | — | — | US | disclosed |
| WO-2014001465-A2 | SOOTHING TOPICAL COMPOSITION CONTAINING PAEONIA AND NYMPHAEA EXTRACTS | SOCIÉTÉ DE RECHERCHE COSMÉTIQUE S.À.R.L. (LU) | 2014-01-03 | — | — | WO | disclosed |
| EP-2111460-A2 | MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA | BIOMERIEUX (FR) | 2009-10-28 | — | — | EP | disclosed |
| WO-2008104679-A2 | MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA | bioMérieux (FR) | 2008-09-04 | — | — | WO | disclosed |
| EP-0366662-A1 | AMINOPEPTIDASE FOR REMOVING N-TERMINAL METHIONINE FROM PROTEINS AND PROTEINS PREPARED THEREFROM | BIOGEN, INC. (US) | 1990-05-09 | — | — | EP | disclosed |