Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232264 | 0.86 | THRB (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL991742 | 0.80 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL3920485 | 0.78 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene SCHEMBL3920482 | 0.77 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL3916830 | 0.76 | THRB (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1554939 | 0.74 | THRB (0.43) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7031855 | 0.73 | TSHR (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL25332 | 0.73 | THRB (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL18051644 | 0.72 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14525085 | 0.72 | TSHR (0.44) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011275-A | Contact lenses, bandages | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4954587-A | CONTACT LENSES | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |