SCHEMBL25332

SCHEMBL25332

C=C(C)C(=O)OCCC([SiH2]O[Si](C)(C)C)([SiH2]O[Si](C)(C)C)[SiH2]O[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3920485 0.76 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL31676655 0.76 TSHR (0.41) THRBTSHRALDH1A1POLBAPEX1
Ethylene SCHEMBL3920482 0.75 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4454148 0.75 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28830566 0.75 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9143876 0.74 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL991742 0.74 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1272771 0.74
SCHEMBL26002227 0.73 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL396936 0.72 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4429816-A1 SYSTEMS AND METHODS FOR LOADING REAGENT-CONTAINING MICROFLUIDIC CHIPS HAVING SINGLE-USE VALVES Pattern Bioscience, Inc. (US) 2024-09-18 EP claimed
US-20230243859-A1 Systems and Methods for Loading Reagent-Containing Microfluidic Chips Having Single-Use Valves PATTERN BIOSCIENCE, INC. (US) 2023-08-03 US claimed
WO-2023084454-A1 SYSTEMS AND METHODS FOR LOADING REAGENT-CONTAINING MICROFLUIDIC CHIPS HAVING SINGLE-USE VALVES PATTERN BIOSCIENCE, INC. (US) 2023-05-19 WO claimed
US-20200166671-A1 LIPOIC ACID HYDROGELS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2020-05-28 US claimed
EP-3640270-A1 LIPOIC ACID HYDROGELS Universidade de Santiago de Compostela (ES) 2020-04-22 EP claimed
US-10406115-B2 Pressure-sensitive adhesives for transdermal drug delivery NOVEN PHARMACEUTICALS, INC. (US) 2019-09-10 US claimed
US-10406116-B2 Pressure-sensitive adhesives for transdermal drug delivery NOVEN PHARMACEUTICALS, INC. (US) 2019-09-10 US claimed
EP-3506889-A1 PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY Noven Pharmaceuticals, INC. (US) 2019-07-10 EP claimed
WO-2018026759-A1 PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2018-02-08 WO claimed
US-20160374954-A1 PRESSURE-SENSITIVE ADHESIVES FOR TRANSDERMAL DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 2016-12-29 US claimed
EP-2314640-B1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS UNIV SANTIAGO COMPOSTELA (ES) 2015-07-01 EP claimed
US-8951548-B2 Acrylic hydrogels with pendant cyclodextrins, preparation method thereof and use of same as release systems and contact lens components UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2015-02-10 US claimed
US-20110200661-A1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2011-08-18 US claimed
EP-2314640-A1 ACRYLIC HYDROGELS WITH PENDANT CYCLODEXTRINS, PREPARATION METHOD THEREOF AND USE OF SAME AS RELEASE SYSTEMS AND CONTACT LENS COMPONENTS Universidade De Santiago De Compostela (ES) 2011-04-27 EP claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed
EP-0455585-B1 Unsaturated urea polysiloxanes CIBA GEIGY AG (CH) 1994-03-23 EP claimed
US-5115056-A FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF CIBA-GEIGY CORPORATION (US) 1992-05-19 US claimed
EP-0455585-A1 Unsaturated urea polysiloxanes CIBA-GEIGY AG (CH) 1991-11-06 EP claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200166671-A1 LIPOIC ACID HYDROGELS CRYAA, CRYAB, CRYZ THRB 2597/4885TSHR 2913/4885ALDH1A1 1326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.