Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859458 | 0.88 | PKM (0.35) | TRPA1ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9861765 | 0.81 | CA2 (0.45) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9861366 | 0.81 | CA1 (0.34) | MAPTNPC1L3MBTL1CA2CA9 | |
| SCHEMBL10501977 | 0.74 | CA2 (0.54) | MEN1KMT2ACA2CA9 | |
| SCHEMBL444673 | 0.72 | TRPA1 (0.48) | TRPA1ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL21178007 | 0.71 | CYP3A4 (0.49) | TRPA1ALDH1A1MAPTLMNAAKT1 | |
| SCHEMBL9861407 | 0.71 | CA2 (0.46) | ALDH1A1SMN1; SMN2L3MBTL1CA2POLB | |
| SCHEMBL9861023 | 0.70 | CA2 (0.61) | ALDH1A1MAPTNPC1LMNAMAPK1 | |
| SCHEMBL9860936 | 0.70 | TRPA1 (0.34) | TRPA1ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL606611 | 0.69 | TRPA1 (0.46) | TRPA1ALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |