SCHEMBL9861014

SCHEMBL9861014

CC(C)(C)c1cc(CSOS(=O)(=O)O)cc(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
RXRA P19793 3/20 0.34
RXRB P28702 3/20 0.34
RXRG P48443 3/20 0.34
ALDH1A1 P00352 2/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
ACLY P53396 1/20 0.31
ELANE P08246 1/20 0.30
CD69 Q07108 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860976 0.83 BCHE (0.48) RXRARXRBALDH1A1BCHEACHE
SCHEMBL10857016 0.77 POLB (0.38) ALDH1A1
SCHEMBL9861052 0.73 SHBG (0.46) ALDH1A1BCHEACHE
SCHEMBL9861771 0.70 IDO1 (0.43) RXRARXRBALDH1A1
SCHEMBL9861031 0.70 BCHE (0.44) ALDH1A1BCHEACHE
SCHEMBL28736653 0.70 IDO1 (0.47) BCHEACHE
SCHEMBL5078812 0.69 CYP2C19 (0.40) ALDH1A1BCHEACHEELANE
SCHEMBL9861772 0.69 TAAR1 (0.47) ALDH1A1
SCHEMBL10708916 0.68 CYP2C19 (0.39) ALDH1A1BCHEACHEELANE
SCHEMBL10709455 0.68 CYP2C19 (0.39) ALDH1A1BCHEACHEELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150168-B1 USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS MONSANTO EUROPE S.A./N.V. (BE) 1991-05-08 EP disclosed
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US disclosed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP disclosed