Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860870 | 0.88 | PTGS2 (0.84) | ALOX5PTGS1PTGS2KMT2AMEN1 | |
| Tebufelone SCHEMBL43674 | 0.79 | PTGS2 (1.00) | ALOX5PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL16284312 | 0.77 | KMT2A (0.39) | PTGS1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9861167 | 0.76 | ALOX5 (0.56) | ALOX5PTGS1PTGS2MAPTCYP2C9 | |
| SCHEMBL7696046 | 0.75 | PTGS2 (0.91) | ALOX5PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL9178091 | 0.74 | PTGS2 (0.61) | ALOX5PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL9420125 | 0.74 | PTGS2 (0.89) | ALOX5PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL7704620 | 0.74 | PTGS2 (0.89) | ALOX5PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL9178540 | 0.73 | PTGS2 (0.60) | ALOX5PTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL9860963 | 0.73 | PTGS2 (0.85) | ALOX5PTGS1PTGS2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4982006-A | Process for the preparation of certain substituted aromatic compounds | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4847303-A | UNSATURATED KETONES | THE PROCTER & GAMBLE COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0321432-A1 | Process for the preparation of certain substituted aromatic compounds | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-06-21 | — | — | EP | disclosed |
| EP-0318090-A2 | Tert-butyl phenyl compounds as anti-inflammatory agents | THE PROCTER & GAMBLE COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |