Methacrylic Acid

Methacrylic Acid

SCHEMBL9861111

C=C(C)C(=O)O.C=CC(F)(F)F

nearest known ligand 0.36

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.32
TET2 Q6N021 1/20 0.31
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28857095 0.81 ALDH1A1 (0.38) ALDH1A1TDP1TP53TSHRLMNA
Methacrylic Acid SCHEMBL2047620 0.80
Methacrylic Acid SCHEMBL28902069 0.80 LMNA (0.48) ALDH1A1TDP1TP53TSHRLMNA
Bicarbonate SCHEMBL319318 0.80 LMNA (0.41) ALDH1A1TSHRLMNA
Bicarbonate SCHEMBL25436122 0.80 LMNA (0.41) ALDH1A1TSHRLMNA
Methacrylic Acid SCHEMBL28434642 0.79 TET2 (0.38) ALDH1A1TDP1TP53TSHRLMNA
Methacrylic Acid SCHEMBL25332376 0.78 THRB (0.35)
Trifluoroacetic Acid SCHEMBL27075743 0.78 TDP1 (0.38) ALDH1A1TDP1TSHRTET2FFAR3
Methacrylic Acid SCHEMBL7597325 0.78 TDP1 (0.38) ALDH1A1TDP1TSHRTET2FFAR3
Methacrylic Acid SCHEMBL28027518 0.78 TDP1 (0.38) ALDH1A1TDP1TET2FFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988771-A Free-radical polymerized fluorine containing olefin monomer SOKEN KAGAKU KABUSHIKI KAISHA (JP) 1991-01-29 US disclosed
US-4916191-A Graft copolymer having dispersion stabilizing effect, a process for producing the same, and a process of emulsion polymerization using the same SOKEN KAGAKU KABUSHIKI KAISHA (JP) 1990-04-10 US disclosed